IMPORTANCE OF CROSSMATCHING
Crossmatching aims to establish a serological compatibility between the recipient and the donor. The classical technology uses an agglutination reaction to detect allo antibodies produced after a previous transfusion and/or the naturally antibodies.
Our immuno-chromatographic technology will detect the presence of immunoglobulin and/or C3 components binding to the red blood cells surface. It indicates an in vitro sensitization and can thus be used to indicate the presence of allo antibodies in pre-transfusion compatibility testing.
This test also allows to detect circulating auto antibodies in the recipient.